Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function

nuri77Overview of the antiinflammatory snaling pathway of the orphan nuclear receptor Nur77 in EC. LPS induces an increase of Nur77 expression that negatively regulates endothelialIntracellular infections by Gram-negative bacteria are a snificant global health threat. The nuclear receptor Nur77 (also called TR3, NGFI-B, or NR4A1) was recently shown